Breast cancer blog from bcancer.com

Time [GMT +0] : 11 Sep , 02:07:23

| | |

16 Sep 2005 12:27:40 pm

Researchers Cure Breast Tumors in Mice Using Vaccine

(Credit for the photograph: Paul Neeson, PhD, University of Pennsylvania School of Medicine.)
Researchers from Pennsylvania School of Medicine were able to cure breast tumors in mice using an experimental cancer vaccine. Using a cancer vaccine based on the bacterium Listeria monocytogenes, they were able to eradicate completely, breast tumors that were present in mice. This vaccine works by boosting an immune response against tumor-associated antigens. In this exciting research led by Yvonne Paterson, PhD, delivered the tumor-associated antigen HER-2/Neu to immune cells. HER-2/Neu is over-expressed in about 20 to 30 percent of all breast cancers. These cells eventually enlist killer T cells to seek out and destroy the tumor cells that display the HER-2/Neu molecule.

"We found that we can stop the tumor from growing out to 100 days, at which time we stopped measuring since this is a long time for experiments of this type," says Paterson. "The tumors stopped growing or went completely away." Researchers have published their findings in the latest issue of The Journal of Immunology.

"The problem that we encounter is that often by the time a patient presents with cancer, they've developed immune tolerance to the tumor antigen, particularly when the antigen is expressed at low levels on normal tissue as with Her2/Neu," explains Paterson. "So how is the body to mount a strong enough immune reaction?"

In general, bacteria are good at inducing both innate and adaptive immune responses, activating such immune cells as macrophages, dendritic cells, and T cells. This helps jump-start the immune response to break tolerance.

Category : General | Posted By : Sherin |

Comments [51] |

Trackbacks [0]

Comments



By : replica watches @ Time : 02 Nov 2009 04:50:53 am


Goofer





By : replica watches @ Time : 02 Nov 2009 07:12:34 am


Goofer





By : replica watches @ Time : 02 Nov 2009 08:32:21 am


Goofer





By : replica watches @ Time : 02 Nov 2009 09:56:19 am


Goofer




replica watch
By : fdsfds @ Time : 04 Nov 2009 05:52:12 am


Goofer




replica watch
By : fdsfds @ Time : 24 Dec 2009 02:23:53 am


Goofer




replica watch
By : osborn @ Time : 02 Jan 2010 07:30:48 am


Goofer




replica watch
By : fdsfds @ Time : 05 Jan 2010 04:56:55 am


Goofer




Replica Watches
By : replica watches @ Time : 15 Jan 2010 10:10:45 am


Goofer




Replica Watches
By : replica watches @ Time : 15 Jan 2010 10:13:14 am


Goofer




Replica Watches
By : replica watches @ Time : 15 Jan 2010 11:00:50 am


Goofer




Replica Watches
By : replica watches @ Time : 15 Jan 2010 11:26:00 am


Goofer




dsgdfgh
By : dfgfdg @ Time : 21 Jan 2010 05:35:53 am


Goofer




SGDFHDH
By : FGH @ Time : 21 Jan 2010 05:36:15 am


Goofer




Replica Watches
By : replica watches @ Time : 19 Mar 2010 09:11:05 am


Goofer




Replica Watches
By : replica watches @ Time : 06 Apr 2010 02:43:17 pm


Goofer




Replica Watches
By : replica watches @ Time : 06 Apr 2010 03:23:37 pm


Goofer




replica watch
By : gzbeads @ Time : 12 Jul 2010 08:59:55 am


Goofer




Great job
By : wow gold @ Time : 12 Jul 2010 10:05:21 am


Goofer




replica watch
By : gzbeads @ Time : 15 Jul 2010 09:59:29 am


Goofer




Wholesale Beads
By : gzbeads @ Time : 21 Jul 2010 03:19:09 pm


Goofer




Replica Watches
By : replica watches @ Time : 27 Jul 2010 04:54:55 pm


Goofer




Replica Watches
By : replica watches @ Time : 28 Jul 2010 07:06:32 am


Goofer




Replica Watches
By : replica watches @ Time : 29 Jul 2010 03:01:28 am


Goofer




Replica Watches
By : replica watches @ Time : 29 Jul 2010 03:02:32 am


Goofer




Replica Watches
By : replica watches @ Time : 29 Jul 2010 03:22:35 am


Goofer




Replica Watches
By : replica watches @ Time : 29 Jul 2010 04:49:37 am


Goofer




Replica Watches
By : replica watches @ Time : 29 Jul 2010 08:43:55 am


Goofer




Replica Watches
By : replica watches @ Time : 30 Jul 2010 09:35:09 am


Goofer




Replica Watches
By : replica watches @ Time : 30 Jul 2010 11:23:40 am


Goofer




Replica Watches
By : replica watches @ Time : 31 Jul 2010 07:59:40 am


Goofer




Replica Watches
By : replica watches @ Time : 31 Jul 2010 11:09:08 am


Goofer




Replica Watches
By : replica watches @ Time : 02 Aug 2010 03:28:09 am


Goofer




Replica Watches
By : replica watches @ Time : 02 Aug 2010 04:31:30 am


Goofer




Replica Watches
By : replica watches @ Time : 02 Aug 2010 04:35:55 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 03:57:04 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 04:00:03 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 04:01:42 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 04:07:58 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 08:07:07 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 09:55:04 am


Goofer




Replica Watches
By : replica watches @ Time : 03 Aug 2010 10:22:02 am


Goofer




Replica Watches
By : replica watches @ Time : 05 Aug 2010 06:48:45 am


Goofer




Replica Watches
By : replica watches @ Time : 05 Aug 2010 09:46:35 am


Goofer




Replica Watches
By : replica watches @ Time : 07 Aug 2010 01:57:40 pm


Goofer




Replica Watches
By : replica watches @ Time : 09 Aug 2010 04:34:04 am


Goofer




Replica Watches
By : replica watches @ Time : 09 Aug 2010 04:52:44 am


Goofer




Replica Watches
By : replica watches @ Time : 09 Aug 2010 07:48:05 am


Goofer




Replica Watches
By : replica watches @ Time : 10 Aug 2010 09:38:02 am


Goofer




wholesale jewelry
By : wholesale jewelry @ Time : 25 Aug 2010 07:25:31 am


Goofer




Wholesale Beads
By : gotowatches @ Time : 04 Sep 2010 03:10:56 am


Goofer

Add Your Comment

	September 2010
S	M	T	W	T	F	S
			1	2	3	4
5	6	7	8	9	10	11
12	13	14	15	16	17	18
19	20	21	22	23	24	25
26	27	28	29	30

Bcancer Main
Message board
Bcancer News

Categories
	Breast cancer treatment	[159]
	General	[144]

Recent
	Cancer In Women With Rare Breast Condition
	Breast Cancer Survivors Have Higher Suicide Rates
	Cosmetic Outcome Of Lumpectomy
	Worried About An Abnormal Mammogram?
	Detecting Early Metastasis Of Breast Cancer
	Bisphenol A And Breast Cancer
	Changing Life Style For Breast Cancer Survivors
	Genes As Predictors Of Breast Cancer
	DNA damage and breast cancer
	Breast Stem Cell Secrets

Archives
	March 2006	[23]
	February 2006	[22]
	January 2006	[23]
	December 2005	[24]
	November 2005	[27]
	October 2005	[27]
	September 2005	[24]
	August 2005	[29]
	July 2005	[10]
	June 2005	[35]
	May 2005	[28]
	April 2005	[31]