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08 Sep 2005 12:12:54 pm

Breast Cancer and African American Women

Breast cancer is the leading cancer site in African American women. Breast cancer is the second leading cause of death among African American women, (exceeded only by lung cancer). Even though incidence of breast cancer is slightly lower in African American women compared to Caucasian women, mortality rate from breast cancer is 28 percent higher in African American women compared to Caucasian women

New research findings suggest that African-American women who carry the 10398A mitochondrial DNA allele are 60 percent more likely to develop invasive breast cancer compared to African-American females without this genetic marker. There were no apparent implications for 10398A mitochondrial DNA for breast cancer in white women.

This study was headed by Jeffrey Canter, M.D., M.P.H., of the Center for Human Genetics Research at Vanderbilt University, Nashville, Tennessee and the research data is published in the September 1 issue of "Cancer Research."

The mitochondria, located outside the nucleus, are the cell's energy-producing factories. Unlike chromosomal DNA, the mitochondrial DNA is passed to offspring exclusively from the mother.

Category : General | Posted By : Sherin |

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